About our product

URIS® isa breakthrough technology for the treatment of diseases associated with Central Nervous System disorders.

The URIS® device operates on a principle of electrical transcutaneous nerve modulation (eTNM®). Through specially designed electrodes, that do not compromise the integrity of the skin, URIS® can selectively stimulate nerve pathways to the brain. Such precisely targeted stimulation activates brain centers that are in decline, or to inhibit overly active brain centers in order to restore balance to the brain.

The URIS® device is the first clinically tested neuromodulation device that uses a closed-loop biofeedback system and is designed to allow treatment from the comfort of one’s home. Patients are provided with a treatment tailored to their conditions without the need to travel to a doctor.

URIS® and a treatment of overactive bladder (OAB)

Our first clinical target was the treatment of OAB, in which we have achieved excellent results. We also expect to achieve similar results in other clinical areas.

Specifically, in the treatment of an overactive bladder, we have observed an 80% reduction in the incidence of undesired episodes of urge to void and a significant activation of brain structures previously involved in the perception of a bladder filling. The stimulation consisted of two parts:

Phase 1: the intensive phase. A patient is stimulated over the course of 6-12 weeks. Stimulation occurs daily for 30 minutes per day. Our device relays data back to doctors allowing them to adjust the stimulation parameters to each patient’s exact needs in order to achieve maximum treatment effectiveness.

Phase 2: the maintenance phase. Stimulation frequency is gradually reduced from daily to weekly stimulations with the goal of eventually only requiring a single stimulation session per month.

According to clinical studies, this is one of the most effective methods of treating OAB, comparable in its effects to an invasive treatment, but with a very few risks and side effects. Only 0.01% of clinical study patients experienced side effects.


URIS® is unique

Learn more about how our technology has helped to improve a quality of life for patients with an overactive bladder disease. Curious about what their life is like after stimulation, what the URIS® treatment itself meant to them, or the results of recent clinical trials?


Our technology aligns with the growing interest in telemedicine. An integral component of this treatment is a mobile app that collects data about each stimulation session and the stimulation efficacy. At the end of each stimulation session the data is sent directly to an attending physician so that the patient’s condition is always monitored, even remotely.

Access to this data also allows for doctors to predict treatment success and facilitates the creation of new treatment parameters. Treatment with our technology is therefore highly responsive to a patient’s real condition and the extent of his or her disease making it highly effective.

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